The Internet of Things (IoT) is transforming the way that organizations communicate, collaborate, and coordinate everyday business and industrial processes. Adoption of IoT technologies has proven well suited to organizations that manage large numbers of assets and coordinate complex and distributed processes. From monitoring machines on a factory floor to tracking supply chains to automating sophisticated, and often dangerous, industrial processes, IoT technologies are optimizing the performance of equipment, improving efficiency, and protecting the safety of workers. Decades ago, the U.S. Department of Defense (DoD) played a critical role in pioneering the sensor, computer networking, and communications technology that serve as the foundation of IoT. In the late 1990s, the Department articulated a vision for “network-centric” warfare that integrated three domains—physical, information, and cognitive—to enhance information sharing and collaboration. Network-centric warfare has been a driving force behind recent defense transformation and has led to the adoption of IoT-related technologies in key areas.